
This article could
have been entitled "Aging: We All Do it, But Why?" Dr. I.N.
Love wrote about this subject in an article entitled, "The Needs and Rights of Old
Age" (JAMA, Nov. 29,1897).
No, the date of Dr. Loves publication in the Journal
of the American Medical Association is not a misprint: it was published over 100
years ago about Sir George Humphreys research on centenarians, that
elite group of people whove made it to 100 years of age.
Sir George concluded that "The prime requisite is
the faculty of age in the blood by inheritance." And Dr. Love added, that "While
heredity is of importance, bear in mind that the deficiencies of heredity can be made up
by correct living."
That was pretty good advice then, and still is. However,
had Dr. Love and Sir George known, as we do today, about our ribosomes
and telomeres (more on these later) they might have held a slightly
different view of what could be done to prolong your life.

The Question?

Since all living things age, the question is: Why
and what can we do about it?
People have been interested in the answer for as long as
human beings have been asking questions. So what do Baltimore, MD, Cambridge, MA, Mankato,
MN, Houston and San Antonio, TX have to do with this? In these cities, and in many others throughout
North America and the world, gerontologists (scientists who study the
aging process) are conducting research on why we age. These scientists
also want to know why we age differently, and what can we learn from studying animals and
older people that can help you have a good old age.

While there are many definitions and theories of
aging, readers can think of their own bodies as becoming increasingly vulnerable
to all sorts of stressors from those things we inherit and from those
things in the environment to which were exposed.

Age Related Changes

So were not surprised when we turn 40 and our
eyesight changes enough for many to need reading glasses or contact lenses: this is called
presbyopia the prefix "presby" meaning old and the
suffix "opia" referring to our eyes. Presbyopia is one of those normal
age-related changes not necessarily caused by any one of a variety of diseases of the eye.
Other changes in the neurosensory system include hearing
loss (presbycusis) and varying degrees of memory impairment. So if you
forget where your car keys are, thats OK; its when you forget that you have a
car, then youve got a problem. But thats not normal aging: thats a dementia
caused by strokes, Alzheimers disease, and other neurological
problems.

Immunity

We experience similar changes in our immune
systems, which can affect the extent to which we fight infectious diseases.
Our production
of antibodies, those soldiers who fight off invading microorganisms and even errant cells
that can become cancerous, is impaired with age.
When a young person gets the flu,
theyre sick for a few days and get better. For an older person, the flu can kill
you. So, just as we get immunizations against childhood diseases like
measles, mumps, chickenpox, etc, older people need immunizations against influenza and
pneumonia.
